The solubility of the cannabinoids found in cannabis allow for them to be extracted with various organic solvents to create concentrated cannabis products. The solvents employed in cannabis manufacturing, primarily hydrocarbons and alcohol, extract cannabinoids from cannabis plant material, while removing particulates, waxes, lipids, fats, and other dissolved impurities.
Except for ethanol, the limits on the amount of solvent residue that can be present in manufactured botanical products are established by the International Conference on Harmonization (ICH). The ICH has determined 3 classes for solvents and requires processors to justify the presence of any detected residue in their final products. The 3 ICH classes are;
In general, samples will fail residual solvent screening if a Class 1, 2, or 3 solvent not listed in the table above is detected above its class limit;